Webster’s Revised Unabridged Dictionary · 1913
Malignance
Ma·lig′nance, Ma·lig′nan·cy, n. [See Malignant.] 1. The state or quality of being malignant; extreme malevolence; bitter enmity; malice; as, malignancy of heart.
2. Unfavorableness; evil nature.
The malignancy of my fate might perhaps distemner yours. Shak.
3. (Med.) Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever.
4. The state of being a malignant.
Syn. — Malice; malevolence; malignity. See Malice.